関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Phenylethanolamine | HCID 1000 | — |
| 反応物 | O-Xylene | HCID 7237 | — |
| 反応物 | 2-Nitroamino-2-imidazoline | HCID 410042 | — |
| 溶媒 | Acetone | HCID 180 | — |
| 生成物 | alpha-(((4,5-Dihydro-1H-imidazol-2-yl)amino)methyl)benzyl alcohol | HCID 103775 | — |
反応手順
A mixture of 15.8 parts β-hydroxy-phenethyl-amine, 13 parts 2-nitramino-2-imidazoline and 8 parts xylene is stirred and heated for 30 minutes at 160°C. (oil-bath). After cooling the reaction mixture to a temperature of about 70°C., there are added 40 parts acetone. The whole is filtered warm and after cooling the filtrate to room temperature, the precipicated product is filtered off and dried, yielding 2-(β-hydroxy-phenethyl-amino)-2-imidazoline; m.p. 147°-149°C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US03983133 |
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| 出典データセット | uspto-grants-1976_09 |
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| ORD ID | ord-89c90c3b4a1241ecba9222bfc6b6ec7a |
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| 出典メモ | uspto-grants-1976_09 |
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