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2-Nitroamino-2-imidazoline → alpha-(2-Imidazolin-2-ylaminomethyl)-m-methylbenzyl alcohol
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2-Nitroamino-2-imidazoline | HCID 410042 | — |
| 反応物 | 2-Amino-1-(3-methylphenyl)ethan-1-ol | HCID 13482511 | — |
| 溶媒 | O-Xylene | HCID 7237 | — |
| 生成物 | alpha-(2-Imidazolin-2-ylaminomethyl)-m-methylbenzyl alcohol | HCID 53888914 | — |
反応手順
A mixture of 8.2 parts of α-(aminomethyl)-m-methylbenzyl alcohol, 6,1 parts of 2-(nitramino)-2-imidazoline and 40 parts of xylene is stirred in an oil-bath at 150°-160°C, while almost all xylene is distilled off. The residue is diluted with a few parts of acetone and allowed to crystallize. The product is filtered off and recrystallized from 4-methyl-2-pentanone, yielding α-(2-imidazolin-2-ylaminomethyl)-m-methylbenzyl alcohol; m.p. 121°C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US03983133 |
| 出典データセット | uspto-grants-1976_09 |
| ORD ID | ord-522e6db6ff9344f395e2cbef978ae442 |
| 出典メモ | uspto-grants-1976_09 |