p-Anisoyl chloride → 5-Chloro-2-phenyl-3-(4-methoxybenzoyl)benzofuran

反応式

[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[O:9][C:8]([C:10]3[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=3)=[CH:7][C:6]=2[CH:16]=1.[C:17](Cl)(=[O:26])[C:18]1[CH:23]=[CH:22][C:21]([O:24][CH3:25])=[CH:20][CH:19]=1>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[O:9][C:8]([C:10]3[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=3)=[C:7]([C:17](=[O:26])[C:18]3[CH:23]=[CH:22][C:21]([O:24][CH3:25])=[CH:20][CH:19]=3)[C:6]=2[CH:16]=1

参加物

反応物 2

HCID 7477p-Anisoyl chloride

HCID 6150425-Chloro-2-phenylbenzofuran

生成物 1

HCID 214353985-Chloro-2-phenyl-3-(4-methoxybenzoyl)benzofuran

実験手順

Acylation of 5-chloro-2-phenylbenzofuran with p-anisoyl chloride was accomplished as described in the procedure of Example 1 to give 5-chloro-2-phenyl-3-(4-methoxybenzoyl)benzofuran which was then demethylated as described above to give 5-chloro-3-(4-hydroxybenzoyl)-2-phenylbenzofuran.

出典と根拠

ORDレコード: ord-3a02ec4ac2224d33b24dba96d31e6f2e
出典データセット: uspto-grants-1976_09
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US03983245

反応ノート

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