Methylamine → N-cyano-N'-[2-(3-isothiazolylmethylthio)ethyl]-N"-methylguanidine
反応式
[C:1]([NH:3][C:4](=[N:7][CH2:8][CH2:9][S:10][CH2:11][C:12]1[CH:16]=[CH:15][S:14][N:13]=1)SC)#[N:2].[CH3:17][NH2:18]>>[C:1]([NH:3][C:4]([NH:7][CH2:8][CH2:9][S:10][CH2:11][C:12]1[CH:16]=[CH:15][S:14][N:13]=1)=[N:18][CH3:17])#[N:2]参加物
3
実験手順
The reaction of N-cyano-N'-[2-(3-isothiazolylmethylthio)ethyl]-S-methylisothiourea (0.27 g.) with excess methylamine according to the procedure described in Example 3(c) and recrystallisation of the product from isopropyl acetate afforded N-cyano-N'-[2-(3-isothiazolylmethylthio)ethyl]-N"-methylguanidine (0.12 g.), m.p. 91°-93°. (Found: C, 42.4; H, 5.1; N, 27.3; S, 25.2. C9H13N5S2 requires: C, 42.3; H, 5.1; N, 27.4; S, 25.1).
後処理
- customdescribed in Example 3(c) and recrystallisation of the product from isopropyl acetate
出典と根拠
- ORDレコード
- ord-c9961a5b966b46a8ab731f812ba0d6ab
- 出典データセット
- uspto-grants-1981_09
- 特許番号
- US04287198
反応ノート
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