(1,4-Diazepan-1-yl)(furan-2-yl)methanone → 1-(Tetrahydrofuran-2-ylcarbonyl)-1,4-diazepane
反応式
[O:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[C:6]([N:8]1[CH2:14][CH2:13][CH2:12][NH:11][CH2:10][CH2:9]1)=[O:7]>[Rh].C(O)C>[O:1]1[CH2:5][CH2:4][CH2:3][CH:2]1[C:6]([N:8]1[CH2:14][CH2:13][CH2:12][NH:11][CH2:10][CH2:9]1)=[O:7]参加物
4
実験手順
N-[2-Furoyl)homopiperazine (33.0 g.) in 200 ml. of ethanol was hydrogenated over 5% rhodium-on-carbon catalyst at three atmospheres pressure. The catalyst was removed by filtration and the product distilled to give the desired product, B.P. 135° at 1 mm.
後処理
- customThe catalyst was removed by filtration
- distillationthe product distilled
出典と根拠
- ORDレコード
- ord-e5523ab9c3474918a87ea1d6a869820d
- 出典データセット
- uspto-grants-1981_09
- 特許番号
- US04287341
反応ノート
読み込み中…