Water → 7-Hydroxy-4-(naphthalen-2-yl)-2H-1-benzopyran-2-one

HRID 1577457

反応式

HRID 1577457 の反応式
[C:1]1([CH:8]=[CH:7][CH:6]=[C:4]([OH:5])[CH:3]=1)[OH:2].[CH:9]1[C:18]2[C:13](=[CH:14][CH:15]=[CH:16][CH:17]=2)[CH:12]=[CH:11][C:10]=1[C:19]([CH2:21][C:22](OCC)=[O:23])=O.O>S(=O)(=O)(O)O>[OH:2][C:1]1[CH:3]=[C:4]2[C:6]([C:19]([C:10]3[CH:11]=[CH:12][C:13]4[C:18](=[CH:17][CH:16]=[CH:15][CH:14]=4)[CH:9]=3)=[CH:21][C:22](=[O:23])[O:5]2)=[CH:7][CH:8]=1

参加物

5

反応物 3

HCID 962WaterHCID 5054ResorcinolHCID 27601583-Naphthalen-2-yl-3-oxopropionic acid ethyl ester

生成物 1

HCID 205704957-Hydroxy-4-(naphthalen-2-yl)-2H-1-benzopyran-2-one収率 26%

試薬・触媒・溶媒 1

HCID 1118Sulfuric Acid溶媒

実験手順

A mixture of resorcinol (11.0 g, 0.1 mole) and ethyl 2-naphthoylacetate (24.2 g, 0.1 mole) in concentrated sulphuric acid (50 ml) was stirred at room temperature for 5 days then poured into water to give a yellow gum. The gum was washed several times with water then dissolved in ethanol and diluted with water to give 7-hydroxy-4-(2-naphthyl)coumarin as a fine pale brown precipitate in 26% yield.

後処理

  1. customto give a yellow gum
  2. washThe gum was washed several times with water
  3. dissolutionthen dissolved in ethanol
  4. additiondiluted with water

出典と根拠

ORDレコード
ord-ea334065d30f4fe4a7009485a8ba293c
出典データセット
uspto-grants-1981_09
特許番号
USRE030739

関連ノート

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