Dimethylamine → HCID 20570904、化合物

HRID 1577500ノート

反応式

HRID 1577500 の反応式
C[O-].[Na+].[CH3:4][CH:5]([C:7]1[CH:11]=[CH:10][O:9][C:8]=1[C:12]([O:14]C)=O)[CH3:6].[CH3:16][NH:17][CH3:18]>CO>[CH3:16][N:17]([CH3:18])[C:12]([C:8]1[O:9][CH:10]=[CH:11][C:7]=1[CH:5]([CH3:6])[CH3:4])=[O:14]

参加物

5

反応物 3

HCID 674DimethylamineHCID 10942334Sodium MethoxideHCID 67355685HCID 67355685、化合物

生成物 1

HCID 20570904HCID 20570904、化合物

試薬・触媒・溶媒 1

HCID 887Methanol溶媒

実験手順

A solution of sodium methoxide (3.3 g) and 3-(1-methylethyl)-2-furancarboxylic acid, methyl ester (14 g) in dry methanol (50 ml) was treated with dimethylamine gas during 2 hours. The solvent was removed in vacuo and the residue was dissolved in diethyl ether (150 ml) and washed with water (100 ml). The ethereal extract was dried over anhydrous sodium sulphate and evaporation of the solvent gave the title compound (12 g) as an oil.

後処理

  1. customThe solvent was removed in vacuo
  2. dissolutionthe residue was dissolved in diethyl ether (150 ml)
  3. washwashed with water (100 ml)
  4. extractionThe ethereal extract
  5. dry with materialwas dried over anhydrous sodium sulphate and evaporation of the solvent

出典と根拠

ORDレコード
ord-48cb1121fc8d471d9d946acb7638b45d
出典データセット
uspto-grants-1981_09
特許番号
US04288443

反応ノート

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