3-Chlorophenyl isothiocyanate → HCID 12783513、化合物

HRID 1577818

反応式

HRID 1577818 の反応式
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]2[NH:13][CH2:12][CH2:11][CH2:10][S:9]2)=[CH:4][CH:3]=1.[Cl:14][C:15]1[CH:16]=[C:17]([N:21]=[C:22]=[S:23])[CH:18]=[CH:19][CH:20]=1>>[Br:1][C:2]1[CH:3]=[CH:4][C:5]([CH:8]2[N:13]([C:22](=[S:23])[NH:21][C:17]3[CH:18]=[CH:19][CH:20]=[C:15]([Cl:14])[CH:16]=3)[CH2:12][CH2:11][CH2:10][S:9]2)=[CH:6][CH:7]=1

参加物

3

反応物 2

HCID 754493-Chlorophenyl isothiocyanateHCID 205696532-(4-bromophenyl)tetrahydro-2H-1,3-thiazine

生成物 1

HCID 12783513HCID 12783513、化合物

実験手順

The procedure of Example 29 was repeated, except that the reactants consisted of 2.6 g. of 2-(4-bromophenyl)tetrahydro-2H-1,3-thiazine and 1.7 g. of 3-chlorophenyl isothiocyanate. The product was isolated by filtration, washed with benzene, and recrystallized from chloroform/benzene,giving 3.7 g. (86%) of 2-(4-bromophenyl)-N-(3-chlorophenyl)tetrahydro-2H-1,3-thiazine-3-carbothioamide, m.p. 144°-6°. The following elemental microanalysis was obtained:

後処理

  1. customThe product was isolated by filtration
  2. washwashed with benzene
  3. customrecrystallized from chloroform/benzene,giving 3.7 g
  4. customThe following elemental microanalysis was obtained

出典と根拠

ORDレコード
ord-39e0e557ae0846dda1141c70616128bf
出典データセット
uspto-grants-1981_09
特許番号
US04289766

関連ノート

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