Benzyl Chloride → 4'-Benzyloxy-2'-hydroxyacetophenone

反応式

[CH2:1](Cl)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.C([O-])([O-])=O.[K+].[K+].C(C1C=CC=CC=1)(=O)C.[CH3:24][C:25]([C:27]1[CH:28]=[CH:29][C:30]([OH:34])=[CH:31][C:32]=1[OH:33])=[O:26]>>[CH3:24][C:25]([C:27]1[CH:28]=[CH:29][C:30]([O:34][CH2:1][C:2]2[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=2)=[CH:31][C:32]=1[OH:33])=[O:26]

参加物

反応物 3

HCID 7503Benzyl Chloride

HCID 11430Potassium Carbonate

HCID 20525554Acetophenone 2,4-dihydroxyacetophenone

生成物 1

HCID 3092574'-Benzyloxy-2'-hydroxyacetophenone

実験手順

The reaction of (1) above is repeated using 1.1 molar equivalents of benzyl chloride, 1.0 molar equivalent of K2CO3, and substituting for the above acetophenone 2,4-dihydroxyacetophenone ##STR19##

出典と根拠

ORDレコード: ord-6591b593e8dd46a3940ddd58f4f51f97
出典データセット: uspto-grants-1981_09
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US04290957

反応ノート

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