化工社化工社 化学情報印刷レポート · 研究参考用
1,1'-Biphenyl, mixt. with 1,1'-oxybis(benzene) → Pregna-4,16-diene-3,20-dione
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1,1'-Biphenyl, mixt. with 1,1'-oxybis(benzene) | HCID 24670 | — |
| 反応物 | Hydroxyprogesterone Caproate | HCID 169870 | — |
| 生成物 | Pregna-4,16-diene-3,20-dione | HCID 101964 | 83% |
反応手順
One gram of 17α-hexanoyloxy-4pregnene-3,20-dione is heated analogously to Example 1 in "Dowtherm" for 80 minutes to 285° C., worked up, separated, and combined. Recrystallization from ethanol yields 600 mg of 4,16-pregnadiene-3,20-dione (83% of theory), m.p. 185°-190° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04290963 |
| 出典データセット | uspto-grants-1981_09 |
| ORD ID | ord-c3f69325bb174eaa9e16edc3a966420d |
| 出典メモ | uspto-grants-1981_09 |