1-Bromo-2-methylpropane → HCID 178475087、化合物

反応式

[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([Cl:8])[C:3]=1[NH:9][C:10]([NH:12][C:13](=[O:15])[CH3:14])=[S:11].C(=O)([O-])[O-].[K+].[K+].[CH2:22](Br)[CH:23]([CH3:25])[CH3:24]>CC(C)=O>[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([Cl:8])[C:3]=1[NH:9][C:10]([NH:12][C:13](=[O:15])[CH3:14])=[SH:11][CH2:22][CH:23]([CH3:25])[CH3:24]

参加物

実験手順

5.2 g (0.02 M) of N-(2,6-dichlorophenyl)-N'-acetylthiourea, 2.1 g (0.015M) of ground potassium carbonate, 3.3 ml (0.03M) of isobutylbromide and 50 ml of acetone were heated together under stirring and reflux for 4 hours. The acetone was then distilled off. The residue in the flask was washed with water and then filtered. 5.9 g (92% of theoretical yield) of N-(2,6-dichlorophenyl)-N'-acetyl-S-isobutyl-thiourea melting at 106° to 112° were obtained. After recrystallization from benzene the product melted at 114° to 116° C.