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2-Methylquinolin-5-yl trifluoromethanesulfonate → 7-Chloro-2-methyl-5-piperazin-1-ylquinoline
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2-Methylquinolin-5-yl trifluoromethanesulfonate | HCID 49851899 | — |
| 反応物 | Tert-butyl 4-(2-methylquinolin-5-yl)piperazine-1-carboxylate | HCID 49851900 | — |
| 反応物 | 2-Methyl-5-piperazin-1-yl-quinoline | HCID 49851901 | — |
| 反応物 | 7-chloro-2-methyl-5-Quinolinol | HCID 135553018 | — |
| 生成物 | 7-Chloro-2-methyl-5-piperazin-1-ylquinoline | HCID 57444275 | — |
反応手順
The title compound was prepared from 7-chloro-5-hydroxy-2-methylquinoline (WO/0234754) using similar procedures to descriptions D1, D2 and D3.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07732600B2 |
| 出典データセット | uspto-grants-2010_06 |
| ORD ID | ord-13294da39753479ab5e595d8d3b068b3 |
| 出典メモ | uspto-grants-2010_06 |