3-Fluoro-4-(methoxycarbonyl)benzeneboronic acid → 3'-Chloro-4'-[2-(1-ethyl-6-oxo-1,6-dihydro-pyridin-3-yl)-3,3,3-trifluoro-2-hydroxy-1-methyl-propyl]-3-fluoro-biphenyl-4-carboxylic acid methyl ester

HRID 157833

反応式

[Br:1][c:2]1[cH:3][c:4]([Cl:25])[c:5]([CH:8]([C:9]([C:10]([F:11])([F:12])[F:13])([OH:14])[c:15]2[cH:16][cH:17][c:18](=[O:23])[n:19]([CH2:21][CH3:22])[cH:20]2)[CH3:24])[cH:6][cH:7]1.[F:26][c:27]1[cH:28][c:29]([B:37]([OH:38])[OH:39])[cH:30][cH:31][c:32]1[C:33](=[O:34])[O:35][CH3:36]>>[c:2]1(-[c:29]2[cH:28][c:27]([F:26])[c:32]([C:33](=[O:34])[O:35][CH3:36])[cH:31][cH:30]2)[cH:3][c:4]([Cl:25])[c:5]([CH:8]([C:9]([C:10]([F:11])([F:12])[F:13])([OH:14])[c:15]2[cH:16][cH:17][c:18](=[O:23])[n:19]([CH2:21][CH3:22])[cH:20]2)[CH3:24])[cH:6][cH:7]1