Ethanol → HCID 178481319、化合物
反応式
[CH3:1][N:2]1[C:6]([N+:7]([O-:9])=[O:8])=[CH:5][N:4]=[C:3]1[C:10](=[NH:14])OCC.C(O)C.[NH2:18][NH:19][C:20]([NH2:22])=[S:21]>C(O)(=O)C>[CH3:1][N:2]1[C:6]([N+:7]([O-:9])=[O:8])=[CH:5][N:4]=[C:3]1[C:10]([NH:18][NH:19][C:20]([NH2:22])=[S:21])=[NH:14]参加物
5
実験手順
To a stirred solution of ethyl 1-methyl-5-nitro-2-imidazolecarboximidate (0.198 g., 0.001 mole) in 10 ml. of absolute ethanol is added thiosemicarbazide (0.091 g., 0.001 mole) and 1 ml. of glacial acetic acid. The mixture is heated at reflux for 1 1/4 hours and is cooled in an ice bath. The orange-red solid is filtered washed and dried affording 0.173 g. of the title compound, melting point 210°-214°, dec.
後処理
- temperatureThe mixture is heated
- temperatureat reflux for 1 1/4 hours
- temperatureis cooled in an ice bath
- filtrationThe orange-red solid is filtered
- washwashed
- customdried
- customaffording 0.173 g
出典と根拠
- ORDレコード
- ord-6329813f9cfa4db28a9d4784c7de66a1
- 出典データセット
- uspto-grants-1976_02
- 特許番号
- US03940411
反応ノート
読み込み中…