Hydrochloric Acid → HCID 21567166、化合物
反応式
[CH3:1][C:2]1[N:3]=[CH:4][C:5]2[C:10]([CH:11]=1)=[C:9]([N+:12]([O-:14])=[O:13])[CH:8]=[CH:7][CH:6]=2.[ClH:15]>>[ClH:15].[CH3:1][C:2]1[N:3]=[CH:4][C:5]2[C:10]([CH:11]=1)=[C:9]([N+:12]([O-:14])=[O:13])[CH:8]=[CH:7][CH:6]=2参加物
3
実験手順
3-methyl-5-nitro-isoquinoline (6 g), prepared according to the method of Example 5 hereinabove, was dissolved in concentrated hydrochloric acid (30 ml). The excess acid was then removed by means of a rotary evaporator, and the residue was digested with boiling ethanol (100 ml). The mixture was cooled and filtered, and the residue was dried in vacuo for several hours, to yield 6.9 g of 3-methyl-5-nitro-isoquinoline hydrochloride melting over a temperature range from 178° to 183°C.
後処理
- customThe excess acid was then removed by means of a rotary evaporator
- temperatureThe mixture was cooled
- filtrationfiltered
- customthe residue was dried in vacuo for several hours
出典と根拠
- ORDレコード
- ord-9ee6f02f5fed4ac4bb2c56c65cb2fe69
- 出典データセット
- uspto-grants-1976_01
- 特許番号
- US03930837
反応ノート
読み込み中…