Acetic Acid → 2-Benzoylbenzaldehyde

HRID 1579513ノート

反応式

HRID 1579513 の反応式
[Se](=O)=O.[OH:4][CH2:5][C:6]1[CH:19]=[CH:18][CH:17]=[CH:16][C:7]=1[CH:8]([OH:15])[C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1.C(O)(=O)C>CC(O)C>[C:8]([C:7]1[CH:16]=[CH:17][CH:18]=[CH:19][C:6]=1[CH:5]=[O:4])(=[O:15])[C:9]1[CH:10]=[CH:11][CH:12]=[CH:13][CH:14]=1

参加物

5

反応物 3

HCID 176Acetic AcidHCID 24007Selenium DioxideHCID 11424431α1-Phenyl-1,2-benzenedimethanol

生成物 1

HCID 1611952-Benzoylbenzaldehyde

試薬・触媒・溶媒 1

HCID 3776Isopropanol溶媒

実験手順

A mixture of 1 g. of selenium dioxide and 1 g. of 2-hydroxymethylbenzhydrol in 5 ml. of acetic acid was refluxed for 41/2 hours. The solution was cooled, filtered from selenium and the filtrate was poured into ice water and made alkaline with sodium hydroxide. Extraction with ether gave a yellow oil to which petroleum ether was added. White prisms were obtained which melted at 64°-67°. Ultraviolet maximum (2-propanol) at 226/7 mμ (ε = 15,750) and 251/2 mμ (ε = 18,500), inflexion at 294 mμ (ε = 2600); infrared absorption (CHCl3) at 1665 cm-1 and 1705 cm-1

後処理

  1. additionA mixture of 1 g
  2. temperatureThe solution was cooled
  3. filtrationfiltered from selenium
  4. additionthe filtrate was poured into ice water
  5. extractionExtraction with ether
  6. customgave a yellow oil to which petroleum ether
  7. additionwas added
  8. customWhite prisms were obtained which melted at 64°-67°
  9. custominfrared absorption (CHCl3) at 1665 cm-1 and 1705 cm-1

出典と根拠

ORDレコード
ord-dbd46268722e4ab7aa321afdae17c09e
出典データセット
uspto-grants-1976_01
特許番号
US03931217

反応ノート

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