3,5-Bis(trifluoromethyl)benzoyl chloride → 2-[3-(3,4-Dichloro-phenyl)-1-(3,5-bis-(trifluoromethyl)-benzoyl)-pyrrolidin-3-yl]-ethanol

反応式

[Cl:1][c:2]1[cH:3][c:4]([C:9]2([CH2:14][CH2:15][OH:16])[CH2:10][NH:11][CH2:12][CH2:13]2)[cH:5][cH:6][c:7]1[Cl:8].[F:17][C:18]([c:19]1[cH:20][c:21]([C:22](=[O:23])[Cl:24])[cH:25][c:26]([C:28]([F:29])([F:30])[F:31])[cH:27]1)([F:32])[F:33]>>[Cl:1][c:2]1[cH:3][c:4]([C:9]2([CH2:14][CH2:15][OH:16])[CH2:10][N:11]([C:22]([c:21]3[cH:20][c:19]([C:18]([F:17])([F:32])[F:33])[cH:27][c:26]([C:28]([F:29])([F:30])[F:31])[cH:25]3)=[O:23])[CH2:12][CH2:13]2)[cH:5][cH:6][c:7]1[Cl:8]

参加物

反応物 2

HCID 1018563,5-Bis(trifluoromethyl)benzoyl chloride

HCID 184644272-(3-(3,4-Dichlorophenyl)pyrrolidin-3-yl)ethanol

生成物 1

HCID 183333612-[3-(3,4-Dichloro-phenyl)-1-(3,5-bis-(trifluoromethyl)-benzoyl)-pyrrolidin-3-yl]-ethanol

出典と根拠

ORDレコード: ord-08c58132e2d24c0889b22a8c8eca4c06
出典データセット: Training data from https://doi.org/10.1039/C8SC04228D (9/10)
DOI: 10.1039/C8SC04228D

反応ノート

読み込み中…