O-Ethyl carbamothioate → 2-Hydroxy-5,6-dihydro-4H-benzothiazol-7-one
反応式
Cl[CH:2]1[C:7](=O)[CH2:6][CH2:5][CH2:4][C:3]1=[O:9].[C:10](=[S:15])([O:12]CC)[NH2:11]>O>[O:9]=[C:3]1[C:2]2[S:15][C:10](=[O:12])[NH:11][C:7]=2[CH2:6][CH2:5][CH2:4]1参加物
4
反応条件
- 温度
- 140 °C
実験手順
A mixture of 29.3 g of 2-chloro-1,3-cyclohexanedione [Muehlstaedt et al, J. Prakt Chem., Vol. 20 (1963), p. 285] and 21 g of ethyl thiocarbamate was heated at 140°C for 15 minutes and was then poured into water. The precipitate formed was recovered by vacuum filtering and was crystallized from isopropyl alcohol to obtain 12.2 g of 7-oxo-2,3,4,5,6,7-hexahydrobenzothiazoline-2-one melting at 262°C.
後処理
- customThe precipitate formed
- customwas recovered by vacuum
- filtrationfiltering
- customwas crystallized from isopropyl alcohol
出典と根拠
- ORDレコード
- ord-9a294540aabe4ec2b63d58a707f0442b
- 出典データセット
- uspto-grants-1976_01
- 特許番号
- US03932433
反応ノート
読み込み中…