Peracetic Acid → HCID 178504624、化合物

反応式

[C:1]1([N:7]2[C:11]([S:12][CH3:13])=[N:10][C:9]([OH:14])=[N:8]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.C(OO)(=[O:17])C>C(OCC)(=O)C.C(O)(=O)C>[C:1]1([N:7]2[C:11]([S:12]([CH3:13])=[O:17])=[N:10][C:9]([OH:14])=[N:8]2)[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

参加物

反応条件

温度: 50 °C

実験手順

An amount of 41.4 g of 1-phenyl-5-methylmercapto-3-hydroxy-1,2,4-triazole is suspended at 50°C in 400 ml of ethyl acetate. An addition is then made dropwise, within 15 minutes, of 60 ml of a 60% solution of peroxyacetic acid in glacial acetic acid at 45°-50°C. After completion of the addition, the solution is stirred for 2 hours at 50°C, and the cooled to 20°C. The precipitated product is filtered off, washed with water, and dried in vacuo. The resulting product is 1-phenyl-5-methylsulphinyl-3-hydroxy-1,2,4-triazole in the form of white crystals, M.P. 180°-182°C.