Thiourea → HCID 18801823、化合物
反応式
Br[CH:2]([C:7](=O)[C:8]1[CH:13]=[CH:12][C:11]([F:14])=[CH:10][CH:9]=1)[CH2:3][C:4]([OH:6])=[O:5].[NH2:16][C:17]([NH2:19])=[S:18]>C(O)(C)C>[NH2:19][C:17]1[S:18][C:2]([CH2:3][C:4]([OH:6])=[O:5])=[C:7]([C:8]2[CH:13]=[CH:12][C:11]([F:14])=[CH:10][CH:9]=2)[N:16]=1参加物
4
実験手順
A mixture of 10 grams of β-bromo-β-p-fluorobenzoyl-propionic acid and 2.77 grams of thio-urea in 60 c.c. of isopropyl alcohol is refluxed for 1 hour. After cooling, the precipitated solid is filtered off and recrystallised from isopropyl alcohol, m.p. 267°-268°C.
後処理
- temperatureAfter cooling
- filtrationthe precipitated solid is filtered off
- customrecrystallised from isopropyl alcohol, m.p. 267°-268°C.
出典と根拠
- ORDレコード
- ord-964fe9f9031344d6b3ec406a8ef840dc
- 出典データセット
- uspto-grants-1976_01
- 特許番号
- US03933838
反応ノート
読み込み中…