Sulfuric Acid → HCID 718193、化合物
反応式
[C:1]([NH:4][C:5]1[CH:10]=[C:9]([O:11][CH3:12])[CH:8]=[CH:7][C:6]=1[O:13][CH3:14])(=[O:3])[CH3:2].S(=O)(=O)(O)O.[Br:20]Br>O>[C:1]([NH:4][C:5]1[CH:10]=[C:9]([O:11][CH3:12])[C:8]([Br:20])=[CH:7][C:6]=1[O:13][CH3:14])(=[O:3])[CH3:2]参加物
5
実験手順
300 Parts of 1-acetylamino-2,5-dimethoxybenzene were introduced at about 5°C in 1500 parts of 95 % sulfuric acid while stirring, 127 Parts of bromine were added dropwise at about 5°C with outside cooling. The mixture was stirred at 20°C for about 3 hours, 6000 parts by volume of water were added dropwise (a temperature of 25°C is not to be exceeded), the precipitate was suction-filtered and dried. 381 parts of 1-acetylamino-2,5-dimethoxy-4-bromobenzene (=90.4 % of the theory) were obtained.
後処理
- stirringThe mixture was stirred at 20°C for about 3 hours
- filtrationwas suction-filtered
- customdried
出典と根拠
- ORDレコード
- ord-678b57731de948c0b82aa471c65c54f9
- 出典データセット
- uspto-grants-1976_01
- 特許番号
- US03933887
反応ノート
読み込み中…