Hydrochloric Acid → HCID 72644366、化合物
反応式
[O:1]=[C:2]1[NH:6][C:5](=[O:7])[C:4](=[CH:8][C:9]2[CH:10]=[CH:11][C:12]([O:21][CH3:22])=[C:13]([CH2:15][C:16]([O:18]CC)=[O:17])[CH:14]=2)[S:3]1.Cl>C(O)(=O)C>[O:1]=[C:2]1[NH:6][C:5](=[O:7])[C:4](=[CH:8][C:9]2[CH:10]=[CH:11][C:12]([O:21][CH3:22])=[C:13]([CH2:15][C:16]([OH:18])=[O:17])[CH:14]=2)[S:3]1参加物
4
実験手順
Ethyl 2-[5-[(2,4-dioxothiazolidin-5-ylidene)methyl]-2-methoxyphenyl]acetate (1.29 g, 4.01 mmol), concentrated hydrochloric acid (20 mL)and acetic acid (20 mL) were mixed and refluxed for 2.5 hours. After allowed to stand for cooling, ice water was added thereto and the precipitated crystals were collected by filtration, washed with water, and then dried to obtain 1.13 g (96%) of title compound as yellow powder.
後処理
- temperaturerefluxed for 2.5 hours
- temperaturefor cooling
- filtrationthe precipitated crystals were collected by filtration
- washwashed with water
- customdried
出典と根拠
- ORDレコード
- ord-9485b8579f564bd6bc7d9e08616292cc
- 出典データセット
- uspto-grants-2004_05
- 特許番号
- US06730687B1
反応ノート
読み込み中…