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(R)-(-)-3-chloromethylsulfinyl-7-fluoro-1-methyl-4-quinolone → 3-Chloromethylthio-7-fluoro-1-methyl-4-quinolone
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | (R)-(-)-3-chloromethylsulfinyl-7-fluoro-1-methyl-4-quinolone | HCID 10445996 | — |
| 反応物 | (S)-(+)-3-chloromethylsulfinyl-7-fluoro-1-methyl-4-quinolone | HCID 10445997 | — |
| 反応物 | 7-Fluoro-1-methyl-3-methylthio-4-quinolone | HCID 86589151 | — |
| 生成物 | 3-Chloromethylthio-7-fluoro-1-methyl-4-quinolone | HCID 10445208 | — |
反応手順
FIG. 9 depicts the second step in the synthesis of e.e.(S)-(+)-3-chloromethylsulfinyl-7-fluoro-1-methyl-4-quinolone and (R)-(−)-3-chloromethylsulfinyl-7-fluoro-1-methyl-4-quinolone. In this step, 7-fluoro-1-methyl-3-methylthio-4-quinolone is chlorinated as described to produce 3-chloromethylthio-7-fluoro-1-methyl-4-quinolone.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06730790B2 |
| 出典データセット | uspto-grants-2004_05 |
| ORD ID | ord-ba704b18a28a44fc8338f68904a66385 |
| 出典メモ | uspto-grants-2004_05 |