Dimethylformamide → 6-Isopropyl-4,4-dimethyl-1-n-propyl-1,2,3,4-tetrahydro-quinoline-8-carbaldehyde

反応式

Br[C:2]1[CH:3]=[C:4]([CH:17]([CH3:19])[CH3:18])[CH:5]=[C:6]2[C:11]=1[N:10]([CH2:12][CH2:13][CH3:14])[CH2:9][CH2:8][C:7]2([CH3:16])[CH3:15].CN(C)[CH:22]=[O:23]>>[CH:17]([C:4]1[CH:5]=[C:6]2[C:11](=[C:2]([CH:22]=[O:23])[CH:3]=1)[N:10]([CH2:12][CH2:13][CH3:14])[CH2:9][CH2:8][C:7]2([CH3:16])[CH3:15])([CH3:19])[CH3:18]

参加物

反応物 2

HCID 6228Dimethylformamide

HCID 227198378-Bromo-6-isopropyl-4,4-dimethyl-1-n-propyl-1,2,3,4-tetrahydro-quinoline2 回

生成物 1

HCID 867594426-Isopropyl-4,4-dimethyl-1-n-propyl-1,2,3,4-tetrahydro-quinoline-8-carbaldehyde

実験手順

Following General Procedure B, 8-bromo-6-isopropyl-4,4-dimethyl-1-n-propyl-1,2,3,4-tetrahydro-quinoline (Intermediate 6, 5.64 g, 19.6 mmol) and N,N-dimethylformamide (6.0 g, 78.5 mmol) were reacted to produce the title compound as a yellow oil.

後処理

customwere reacted

出典と根拠

ORDレコード: ord-5b426c243fc04f7e8745051638f1fd97
出典データセット: uspto-grants-2004_05
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US06734193B1

反応ノート

読み込み中…

参加物