1-Chloro-2-phenylethane → 1-(5-chloro-2-(phenethyloxy)phenyl)-1-cyclopropyl-2-(1H-1-imidazolyl)-1-ethanol
反応式
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([OH:8])=[C:4]([C:9]([CH:17]2[CH2:19][CH2:18]2)([OH:16])[CH2:10][N:11]2[CH:15]=[CH:14][N:13]=[CH:12]2)[CH:3]=1.[CH2:20](Cl)[CH2:21][C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1>>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([O:8][CH2:20][CH2:21][C:22]2[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=2)=[C:4]([C:9]([CH:17]2[CH2:19][CH2:18]2)([OH:16])[CH2:10][N:11]2[CH:15]=[CH:14][N:13]=[CH:12]2)[CH:3]=1参加物
3
実験手順
The general procedure of Example 6 was repeated using 4-chloro-2-(1-cyclopropyl-1-hydroxy-2-(1H-1-imidazolyl)ethyl)phenol [compound (2-3)] and phenethyl chloride, to thereby yield 1-(5-chloro-2-(phenethyloxy)phenyl)-1-cyclopropyl-2-(1H-1-imidazolyl)-1-ethanol as colorless crystals (yield: 26.4%).
出典と根拠
- ORDレコード
- ord-b4289f35ac3e49239e7a3376ec00dc88
- 出典データセット
- uspto-grants-2004_05