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HRID 1582822作成日:2026年10月27日

Ethyl 2-(3,3,4,4,5,5,6,6,6-nonafluorohexyl)-8-nonenoate → 10-[3,17beta-Dihydroxyestra-1,3,5(10)-trien-7alpha-yl]-2-(3,3,4,4,5,5,6,6,6-nonafluorohexyl)decanoic acid

https://huagongshe.com/reaction/1582822

反応式

関与物質

役割名称HCID仕込み量
反応物Ethyl 2-(3,3,4,4,5,5,6,6,6-nonafluorohexyl)-8-nonenoateHCID 12048018—
反応物3-Methoxy-7alpha-(2-propenyl)estra-1,3,5(10)-trien-17beta-olHCID 69414807—
生成物10-[3,17beta-Dihydroxyestra-1,3,5(10)-trien-7alpha-yl]-2-(3,3,4,4,5,5,6,6,6-nonafluorohexyl)decanoic acidHCID 53318530—

反応手順

Starting with the 3-methoxy-7α-(2-propenyl)estra-1,3,5(10)-trien-17β-ol prepared in Example 13 and ethyl 2-(3,3,4,4,5,5,6,6,6-nonafluorohexyl)-8-nonenoate prepared separately, the same procedure as shown in Example 13 was repeated to give 10-[3,17β-dihydroxyestra-1,3,5(10)-trien-7α-yl]-2-(3,3,4,4,5,5,6,6,6-nonafluorohexyl)decanoic acid.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US06737417B2
出典データセットuspto-grants-2004_05
ORD IDord-8af89f346de045ffa6b99b0b79a761ca
出典メモuspto-grants-2004_05