Trifluoroacetic anhydride → HCID 21866554、化合物

反応式

[NH2:1][CH2:2][C:3]1[S:7][C:6]([C:8]#[N:9])=[C:5](C)[CH:4]=1.[Cl:11]C1C=CSC=1C#N.[Cl:19]C1C=CSC=1C(N)=O.FC(F)(F)C(OC(=O)C(F)(F)F)=O>>[ClH:11].[NH2:1][CH2:2][C:3]1[S:7][C:6]([C:8]#[N:9])=[C:5]([Cl:19])[CH:4]=1

参加物

反応物 4

HCID 9845Trifluoroacetic anhydride

HCID 27574383-Chloro-2-cyanothiophene

HCID 28080883-Chloro-2-thiophenecarboxamide

HCID 218664655-(Aminomethyl)-3-methyl-2-thiophenecarbonitrile

生成物 1

HCID 21866554HCID 21866554、化合物

実験手順

This compound was synthesized as described for 5-aminomethyl-3-methylthiophene-2-carbonitrile, the 3-chloro-2-cyanothiophene employed having been prepared by dehydrating 3-chlorothiophene-2-carboxamide with trifluoroacetic anhydride.

後処理

customThis compound was synthesized

出典と根拠

ORDレコード: ord-8c4551f494d1457c9d3f7e84ebbd7141
出典データセット: uspto-grants-2004_05
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US06740647B1

反応ノート

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