1-Butanol → HCID 178454803、化合物

HRID 1583731ノート

反応式

HRID 1583731 の反応式
[OH:1][CH:2]([PH:4](=[O:6])[OH:5])[CH3:3].[CH2:7](O)[CH2:8][CH2:9][CH3:10].O>C1C=CC=CC=1>[OH:1][CH:2]([PH:4](=[O:5])[O:6][CH2:7][CH2:8][CH2:9][CH3:10])[CH3:3]

参加物

5

反応物 3

HCID 2631-ButanolHCID 962WaterHCID 178476830HCID 178476830、化合物

生成物 1

HCID 178454803HCID 178454803、化合物収率 81.6%

試薬・触媒・溶媒 1

HCID 241Benzene溶媒

実験手順

A solution of α-hydroxyethylphosphinic acid (2.2 g) and 1-butanol (5.0 g) in benzene (30 ml) was heated for 3 hours with removal of water through a Dean-Stark apparatus. After cooling, the reaction mixture was washed with water, dried over magnesium sulfate and concentrated in vacuo to give 2.71 g (81.6%) of n-butyl α-hydroxyethylphosphinate (Compound No. 5).

後処理

  1. temperatureAfter cooling
  2. washthe reaction mixture was washed with water
  3. dry with materialdried over magnesium sulfate
  4. concentrationconcentrated in vacuo

出典と根拠

ORDレコード
ord-b4d1c7115b5d49439144f548dd9ea9fa
出典データセット
uspto-grants-1985_11
特許番号
US04554111

反応ノート

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