Hydrochloric Acid → 2-Amino-5-tert-butyl-4-(hexadecyloxy)phenol--hydrogen chloride (1/1)

HRID 1583920ノート

反応式

HRID 1583920 の反応式
[C:1]([C:5]1[C:14]([O:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH3:31])=[CH:13][C:8]2[N:9]=C(C)[O:11][C:7]=2[CH:6]=1)([CH3:4])([CH3:3])[CH3:2].[ClH:32]>C(O)C>[ClH:32].[NH2:9][C:8]1[CH:13]=[C:14]([O:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH3:31])[C:5]([C:1]([CH3:4])([CH3:3])[CH3:2])=[CH:6][C:7]=1[OH:11]

参加物

4

反応物 2

HCID 313Hydrochloric AcidHCID 13076757HCID 13076757、化合物

生成物 1

HCID 130767632-Amino-5-tert-butyl-4-(hexadecyloxy)phenol--hydrogen chloride (1/1)収率 92%

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

7.3 g of the benzoxazole compound obtained in Step (d) above was refluxed for 3 hours together with 30 ml of ethanol and 20 ml of concentrated hydrochloric acid. After the completion of the reaction, the reaction mixture was allowed to stand and cool. The crystals thus precipitated were collected by filtration, washed with water and then washed with acetone. Thus, 6.9 g (92% yield) of 2-amino-5-tert-butyl-4-hexadecyloxyphenol hydrochloride was obtained.

後処理

  1. customAfter the completion of the reaction
  2. temperaturecool
  3. customThe crystals thus precipitated
  4. filtrationwere collected by filtration
  5. washwashed with water
  6. washwashed with acetone

出典と根拠

ORDレコード
ord-9ae93751bd5944c3a27a1a3af9a0712a
出典データセット
uspto-grants-1985_11
特許番号
US04555470

反応ノート

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