Ammonia → HCID 70478397、化合物
反応式
C([O:3][C:4](=O)[CH2:5][O:6][C:7]1[CH:12]=[CH:11][C:10]([CH2:13][C:14]2[NH:15][CH:16]=[CH:17][N:18]=2)=[CH:9][CH:8]=1)C.[NH3:20]>C(O)C>[NH:18]1[CH:17]=[CH:16][N:15]=[C:14]1[CH2:13][C:10]1[CH:11]=[CH:12][C:7]([O:6][CH2:5][C:4]([NH2:20])=[O:3])=[CH:8][CH:9]=1参加物
4
実験手順
A solution of 4-(1-imidazolylmethyl)phenoxyacetic acid ethyl ester (2.0 g) in ethanol (10 ml) and concentrated aqueous ammonia (SG 0.880) were heated under reflux for 2 hours and then evaporated. The residue was crystallised from a mixture of methanol and 2-butanone to give 4-(1-imidazolylmethyl)phenoxyacetamide (1.31 g) m.p. 173°-174° C. Found: C, 62.42, H, 5.76, N, 17.40. C12H13N3O2 requires: C, 62.32, H, 5.67, N, 18.17%.
後処理
- temperatureunder reflux for 2 hours
- customevaporated
- customThe residue was crystallised from a mixture of methanol and 2-butanone
出典と根拠
- ORDレコード
- ord-fe754870a2eb4fc08192bd769011abe7
- 出典データセット
- uspto-grants-1985_11
- 特許番号
- US04555516
反応ノート
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