[5-(5-Methyl-tetrazol-1-yl)-benzofuran-7-yl]-methanol → 5-(5-Methyl-tetrazol-1-yl)-benzofuran-7-carbaldehyde
反応式
[CH3:1][C:2]1[N:6]([C:7]2[CH:8]=[C:9]([CH2:16][OH:17])[C:10]3[O:14][CH:13]=[CH:12][C:11]=3[CH:15]=2)[N:5]=[N:4][N:3]=1>O1CCOCC1.[O-2].[Mn+4].[O-2]>[CH3:1][C:2]1[N:6]([C:7]2[CH:8]=[C:9]([CH:16]=[O:17])[C:10]3[O:14][CH:13]=[CH:12][C:11]=3[CH:15]=2)[N:5]=[N:4][N:3]=1参加物
4
実験手順
[5-(5-Methyl-tetrazol-1-yl)-benzofuran-7-yl]-methanol (124 mg,) and manganese (IV) oxide (140 mg) in 1,4-dioxan (5 ml) was heated at reflux for 18 h. A further portion of manganese (IV) oxide (210 mg) was added and heating continued for 2 h. The reaction mixture was filtered through a plug of Hyflo, the pad was washed with chloroform (20 ml) and the filtrate was evaporated in vacuo to give the title compound as a white powder (77 mg).