Ethanol → 1-(2,6-Dichloro-3-pyridylmethyl)amino-1-methylamino-2-nitroethylene

反応式

[Cl:1][C:2]1[C:7]([CH2:8][NH2:9])=[CH:6][CH:5]=[C:4]([Cl:10])[N:3]=1.C[C:12]([NH2:19])(SC)[CH2:13][N+:14]([O-:16])=[O:15].[CH3:20]CO>>[Cl:1][C:2]1[C:7]([CH2:8][NH:9][C:12]([NH:19][CH3:20])=[CH:13][N+:14]([O-:16])=[O:15])=[CH:6][CH:5]=[C:4]([Cl:10])[N:3]=1

参加物

反応物 3

HCID 702Ethanol

HCID 15477284(2,6-Dichloropyridin-3-YL)methanamine

HCID 224505461-Methyl-amino-1-methylthio-2-nitroethane

生成物 1

HCID 598966091-(2,6-Dichloro-3-pyridylmethyl)amino-1-methylamino-2-nitroethylene

実験手順

A mixture of 1.2 g (0.007 mole) of (2,6-dichloro-3-pyridylmethyl)amine and 1 g (0.007 mole) of 1-methyl- amino-1-methylthio-2-nitroethane was refluxed in 50 ml of EtOH for 6 hours. After cooling, the reaction mixture was concentrated and the resulting crystals were collected by filtration, washed with CH2Cl2 and a small amount of EtOH in that order and dried. The procedure gave 0.53 g of the title compound as a white powder.