HCID 178478181、化合物 → HCID 178478548、化合物

HRID 1586363ノート

反応式

HRID 1586363 の反応式
[Cl:1][C:2]1[C:3]([C:7]2[CH:12]=[C:11]([Cl:13])[CH:10]=[C:9]([Cl:14])[CH:8]=2)=[N:4][NH:5][CH:6]=1>C(OCC)C>[ClH:1].[Cl:1][C:2]1[C:3]([C:7]2[CH:8]=[C:9]([Cl:14])[CH:10]=[C:11]([Cl:13])[CH:12]=2)=[N:4][NH:5][CH:6]=1.[Cl:1][C:2]1[C:3]([C:7]2[CH:8]=[C:9]([Cl:14])[CH:10]=[C:11]([Cl:13])[CH:12]=2)=[N:4][NH:5][CH:6]=1

参加物

3

反応物 1

HCID 178478181HCID 178478181、化合物

生成物 1

HCID 178478548HCID 178478548、化合物収率 77.6%

試薬・触媒・溶媒 1

HCID 3283Diethyl Ether溶媒

実験手順

2 g (0.008 mol) of 4-chloro-3-(3,5-dichlorophenyl)pyrazole are dissolved, at room temperature and with stirring, in 200 ml of diethyl ether. Sparging with hydrochloric acid is then carried out until precipitation has ended. The white solid is filtered and rinsed with ether to give 1.1 g (yield 52%, melting point: 175° C.) of 4-chloro-3-(3,5-dichlorophenyl)pyrazole hemihydrochloride.

後処理

  1. customSparging with hydrochloric acid
  2. customis then carried out until precipitation
  3. filtrationThe white solid is filtered
  4. washrinsed with ether

出典と根拠

ORDレコード
ord-08857daf80a943b09997e599523ac755
出典データセット
uspto-grants-1999_08
特許番号
US05945382

反応ノート

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