Sulfuric Acid → Benzenamine, 2-[(1H-benzimidazol-2-ylthio)methyl]-

HRID 1586465ノート

反応式

HRID 1586465 の反応式
[SH:1][C:2]1[NH:3][C:4]2[CH:10]=[CH:9][CH:8]=[CH:7][C:5]=2[N:6]=1.[NH2:11][C:12]1[CH:19]=[CH:18][CH:17]=[CH:16][C:13]=1[CH2:14]O.S(=O)(=O)(O)O.O.C1(N)C=CC=CC=1.C1(N)C=CC=CC=1>C(O)(=O)C>[NH:3]1[C:4]2[CH:10]=[CH:9][CH:8]=[CH:7][C:5]=2[N:6]=[C:2]1[S:1][CH2:14][C:13]1[CH:16]=[CH:17][CH:18]=[CH:19][C:12]=1[NH2:11]

参加物

6

反応物 4

HCID 1118Sulfuric Acid2 回HCID 214392-Aminobenzyl alcohol2 回HCID 69793239HCID 69793239、化合物HCID 178527775HCID 178527775、化合物

生成物 1

HCID 11054238Benzenamine, 2-[(1H-benzimidazol-2-ylthio)methyl]-

試薬・触媒・溶媒 1

HCID 176Acetic Acid溶媒

実験手順

A mixture of 9.0 g (60 mMol) of 2-mercaptobenzimidazole and 4.9 g (40 mMol) of 2-aminobenzyl alcohol were heated at 84° C. in a mixture of 45 ml of glacial acetic acid and 12.0 g (120 mMol) of sulfuric acid. After two hours an additional 1 g (8 mMol) of 2-aminobenzyl alcohol and 1 g of sulfuric acid were added. After one hour the reaction mixture was cooled and poured into cold benzenamine hemihydrate.

後処理

  1. temperatureAfter one hour the reaction mixture was cooled

出典と根拠

ORDレコード
ord-4f4360a0d1a74c708a6edd237279810f
出典データセット
uspto-grants-1999_08
特許番号
US05945425

反応ノート

読み込み中…