化工社化工社 化学情報印刷レポート · 研究参考用
Carbon Tetrachloride → Ethyl 3-bromo-6-methoxy-2-methylbenzoate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Carbon Tetrachloride | HCID 5943 | — |
| 反応物 | Bromine | HCID 24408 | — |
| 反応物 | 2-Methoxy-6-methyl-benzoic acid ethyl ester | HCID 591060 | — |
| 溶媒 | Water | HCID 962 | — |
| 生成物 | Ethyl 3-bromo-6-methoxy-2-methylbenzoate | HCID 11022052 | — |
反応手順
A mixture of ethyl 6-methyl-2-methoxybenzoate (8.4 g, 43.2 mmol), bromine (6.9 g, 43.2 mmol) and tetrachloromethane (170 ml) is stirred at room temperature for 60 hours. The reaction mixture is poured into water and extracted with ethyl acetate. The organic phase is separated and concentrated. The crude product is obtained as a yellow oil, 10.3 g (87% y) and is used without further purification.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05945567 |
| 出典データセット | uspto-grants-1999_08 |
| ORD ID | ord-764df8cc1a0c436faa7522f56ba7521e |
| 出典メモ | uspto-grants-1999_08 |