HCID 19759893、化合物 → HCID 19759913、化合物
反応式
NCC1(C)S(=O)(=O)C2SC=CC=2C1.[CH2:14]([C:17]1([C:27]([NH2:29])=O)[S:24](=[O:26])(=[O:25])[C:20]2[S:21][CH:22]=[CH:23][C:19]=2[CH2:18]1)[CH2:15][CH3:16]>>[NH2:29][CH2:27][C:17]1([CH2:14][CH2:15][CH3:16])[S:24](=[O:26])(=[O:25])[C:20]2[S:21][CH:22]=[CH:23][C:19]=2[CH2:18]1参加物
3
実験手順
The title compound was prepared substantially the same as 2-aminomethyl-2,3-dihydro-2-methylthieno[2,3-b]thiophene-1,1-dioxide. Thus, 2,3-dihydro-2-n-propylthieno[2,3-b]thiophene-2-carboxamide-1,1-dioxide (5.45 g, 21.0 mmol) reacted with borane-dimethyl sulfide complex (21 mL, 10M) to give, after work up, the title compound (4.0 g, 77%). 1H NMR (300 MHz,DMSO-d6) 0.95(t,3H), 1.35(m,2H), 1.80(m,1H), 2.00(m,1H), 2.80(d,1H), 2.95(d,1H), 3.10(d,1H), 3.23(d,1H), 7.05(d,1H), 8.05(d,1H).
後処理
- customto give
出典と根拠
- ORDレコード
- ord-891522f6c4c2412f88c0bc5e77ac5b9f
- 出典データセット
- uspto-grants-1993_06
- 特許番号
- US05216020
反応ノート
読み込み中…