反応式
Br[C:2]1[CH:3]=[CH:4][C:5]([F:27])=[C:6]([CH2:8][CH2:9][N:10]2[CH2:15][CH2:14][N:13]([C:16]3[CH:25]=[CH:24][CH:23]=[C:22]4[C:17]=3[CH:18]=[CH:19][C:20]([CH3:26])=[N:21]4)[CH2:12][CH2:11]2)[CH:7]=1.[CH3:28][C:29]([CH3:34])([CH3:33])[C:30]([NH2:32])=[O:31]>>[F:27][C:5]1[CH:4]=[CH:3][C:2]([NH:32][C:30](=[O:31])[C:29]([CH3:34])([CH3:33])[CH3:28])=[CH:7][C:6]=1[CH2:8][CH2:9][N:10]1[CH2:15][CH2:14][N:13]([C:16]2[CH:25]=[CH:24][CH:23]=[C:22]3[C:17]=2[CH:18]=[CH:19][C:20]([CH3:26])=[N:21]3)[CH2:12][CH2:11]1参加物
3
実験手順
The title compound was prepared in 52% yield according to the general procedure for the preparation of amides, ureas and carbamates (Method A) starting from 5-{4-[2-(5-bromo-2-fluorophenyl)ethyl]-1-piperazinyl}-2-methylquinoline and 2,2-dimethylpropanamide.
出典と根拠
- ORDレコード
- ord-c28b54965a6b4f309b805380e3a65a6d
- 出典データセット
- uspto-grants-2010_06
- 特許番号
- US07732600B2
関連ノート
読み込み中…