Benzene → 2H-Chromen-2-ol
反応式
[OH2:1].[C:2]1([CH3:12])[CH:7]=[CH:6][C:5](S(O)(=O)=O)=[CH:4][CH:3]=1.[OH2:13].[CH:14]1[CH:19]=CC=CC=1>>[O:1]1[C:3]2[CH:4]=[CH:5][CH:6]=[CH:7][C:2]=2[CH:12]=[CH:14][CH:19]1[OH:13]参加物
4
実験手順
The above oil is very oxidatively unstable and was immediately dissolved in about 200 ml of benzene containing p-toluenesulfonic acid monohydrate (500 mg, 2.63 mmole). The benzene solution was heated for about 2 hours under reflux with water removal facilitated by a Dean-Stark apparatus. The cooled benzene mixture was washed with aqueous NaHCO3, dried (brine, MgSO4) and stripped in vacuo to give crude [12a] isolated as a dark gum (4.86 g).
後処理
- washThe cooled benzene mixture was washed with aqueous NaHCO3
- dry with materialdried (brine, MgSO4)
出典と根拠
- ORDレコード
- ord-da9e4cde35a941f0b795ef77e67a6833
- 出典データセット
- uspto-grants-1993_06
- 特許番号
- US05217992
反応ノート
読み込み中…