Zinc Acetate → ZINC 4-methylpicolinate

HRID 1587702

反応式

HRID 1587702 の反応式
[CH3:1][C:2]1[CH:7]=[CH:6][N:5]=[C:4]([C:8]([OH:10])=[O:9])[CH:3]=1.C([O-])(=O)C.[Zn+2:15].C([O-])(=O)C>O>[CH3:1][C:2]1[CH:7]=[CH:6][N:5]=[C:4]([C:8]([O-:10])=[O:9])[CH:3]=1.[Zn+2:15].[CH3:1][C:2]1[CH:7]=[CH:6][N:5]=[C:4]([C:8]([O-:10])=[O:9])[CH:3]=1

参加物

4

反応物 2

HCID 11192Zinc AcetateHCID 27628204-Methylpyridine-2-carboxylic acid

生成物 1

HCID 67852794ZINC 4-methylpicolinate収率 82.3%

試薬・触媒・溶媒 1

HCID 962Water溶媒2 回

実験手順

To a solution of 0.49 g (3.6 mmol) of 4-methylpicolinic acid dissolved in 2.5 ml of water, a solution of 0.40 g (1.8 mmol) of zinc acetate.dihydrate dissolved in 1.5 ml of water was dropwise added while stirring. After the dropwise addition, the mixture was stirred at room temperature for one hour. Because no solid was precipitated, the mixture was evaporated to dryness under a reduced pressure, and the solid obtained was washed with acetone under heating to give 0.50 g of the desired zinc salt. No recrystallization was possible from either water or ethanol (yield 79.1%).

後処理

  1. additionwas dropwise added
  2. additionAfter the dropwise addition
  3. stirringthe mixture was stirred at room temperature for one hour
  4. customBecause no solid was precipitated
  5. customthe mixture was evaporated to dryness under a reduced pressure
  6. customthe solid obtained
  7. washwas washed with acetone
  8. temperatureunder heating

出典と根拠

ORDレコード
ord-5aa083d5bcf040dbb50bf296d63dd46c
出典データセット
uspto-grants-1993_06
特許番号
US05219847

関連ノート

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