Water → 1-(4-Isopropylphenyliminomethyl)-2-nitroiminoimidazolidine

HRID 1587738

反応式

HRID 1587738 の反応式
S(=O)(=O)(O)O.[CH:6]([C:9]1[CH:15]=[CH:14][C:12]([NH2:13])=[CH:11][CH:10]=1)([CH3:8])[CH3:7].CN1CCN(C)C1=O.O.C(O[CH:28](OCC)[N:29]1[CH2:33][CH2:32][NH:31][C:30]1=[N:34][N+:35]([O-:37])=[O:36])C>>[CH:6]([C:9]1[CH:15]=[CH:14][C:12]([N:13]=[CH:28][N:29]2[CH2:33][CH2:32][NH:31][C:30]2=[N:34][N+:35]([O-:37])=[O:36])=[CH:11][CH:10]=1)([CH3:8])[CH3:7]

参加物

6

反応物 5

HCID 962WaterHCID 1118Sulfuric AcidHCID 66611,3-Dimethyl-2-imidazolidinoneHCID 74644-IsopropylanilineHCID 1364034191-Diethoxymethyl-2-nitroiminoimidazolidine

生成物 1

HCID 1363314851-(4-Isopropylphenyliminomethyl)-2-nitroiminoimidazolidine収率 41.6%

実験手順

0.05 g of concentrated sulfuric acid was dropped in a mixture of 5.0 g of 1-diethoxymethyl-2-nitroiminoimidazolidine, 2.48 g of p-isopropylaniline and 2 ml of 1,3-dimethyl-2-imidazolidinone at 110° C., followed by agitation at the same temperature for 1 hour. The reaction mixture was poured into water, extracted with ethyl acetate, washed with water, dried and evaporated. Ether was added to the resultant oily residue and the resultant crystals were separated by filtration and dried to obtain 2.1 g of 1-(4-isopropylphenyliminomethyl)-2-nitroiminoimidazolidine.

後処理

  1. extractionextracted with ethyl acetate
  2. washwashed with water
  3. customdried
  4. customevaporated
  5. additionEther was added to the resultant oily residue
  6. customthe resultant crystals were separated by filtration
  7. customdried

出典と根拠

ORDレコード
ord-90ef4de4147945ed80cb39b27f60a45d
出典データセット
uspto-grants-1993_06
特許番号
US05219868

関連ノート

読み込み中…