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2-Pyrrolidone → 1-[3-(2-Hydroxyethyl)phenyl]-2-pyrrolidinone
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2-Pyrrolidone | HCID 12025 | — |
| 反応物 | 2-(3-Bromophenyl)ethan-1-ol | HCID 2734090 | — |
| 生成物 | 1-[3-(2-Hydroxyethyl)phenyl]-2-pyrrolidinone | HCID 57444361 | 15% |
反応手順
The title compound was prepared in 15% yield according to the general procedure for the preparation of the amides, ureas and carbamates (Method A) starting from 2-(3-bromophenyl)ethanol and 2-pyrrolidinone. Purification was achieved by flash chromatography on silica gel eluting with ethyl acetate.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07732600B2 |
| 出典データセット | uspto-grants-2010_06 |
| ORD ID | ord-bbab621c1e3b4c94b45ab537ff5a5d8b |
| 出典メモ | uspto-grants-2010_06 |