Methylhydrazine → HCID 9903609、化合物

HRID 1588337ノート

反応式

HRID 1588337 の反応式
[O:1]=[C:2]1[NH:7][C:6]2[CH:8]=[CH:9][C:10]([C:12](=O)[CH:13]([CH3:18])[CH2:14][C:15](O)=[O:16])=[CH:11][C:5]=2[O:4][CH2:3]1.[CH3:20][NH:21][NH2:22]>C(O)C>[O:1]=[C:2]1[NH:7][C:6]2[CH:8]=[CH:9][C:10]([C:12]3[CH:13]([CH3:18])[CH2:14][C:15](=[O:16])[N:21]([CH3:20])[N:22]=3)=[CH:11][C:5]=2[O:4][CH2:3]1

参加物

4

反応物 2

HCID 6061MethylhydrazineHCID 11065271HCID 11065271、化合物

生成物 1

HCID 9903609HCID 9903609、化合物

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

4-(3,4-Dihydro-3-oxo-1,4(2H)-benzoxazin-7-yl)-4-oxo-3-methylbutyric acid (1.56 g, 6.0 mmoles) was dissolved in ethanol (300 ml) and methylhydrazine (0.33 ml, 6.0 mmoles) was added. The mixture was heated at reflux for 2 hours, and then cooled to yield to yield the titled compound. The crystals were collected by filtration, recrystallized from ethanol, and recollected by filtration. The solid was dried under vacuum to yield 1.0 g of the titled compound, mp 204°-206° C.

後処理

  1. temperatureThe mixture was heated
  2. temperatureat reflux for 2 hours
  3. temperaturecooled
  4. customto yield

出典と根拠

ORDレコード
ord-ab293ee570ac4156938e385ba76c9c40
出典データセット
uspto-grants-1993_06
特許番号
US05221742

反応ノート

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