2-Methoxy-4-(methylthio)benzoyl chloride → 4-(2-Methoxy-4-methylmercapto-benzoylamino)-5-nitro-1H-pyridin-2-one

HRID 1589295ノート

反応式

HRID 1589295 の反応式
[NH2:1][C:2]1[C:7]([N+:8]([O-:10])=[O:9])=[CH:6][NH:5][C:4](=[O:11])[CH:3]=1.[CH3:12][O:13][C:14]1[CH:22]=[C:21]([S:23][CH3:24])[CH:20]=[CH:19][C:15]=1[C:16](Cl)=[O:17]>ClC1C=CC=CC=1>[CH3:12][O:13][C:14]1[CH:22]=[C:21]([S:23][CH3:24])[CH:20]=[CH:19][C:15]=1[C:16]([NH:1][C:2]1[C:7]([N+:8]([O-:10])=[O:9])=[CH:6][NH:5][C:4](=[O:11])[CH:3]=1)=[O:17]

参加物

4

反応物 2

HCID 27595912-Methoxy-4-(methylthio)benzoyl chlorideHCID 135209334-Amino-5-nitro-2-pyridinol

生成物 1

HCID 135209344-(2-Methoxy-4-methylmercapto-benzoylamino)-5-nitro-1H-pyridin-2-one

試薬・触媒・溶媒 1

HCID 7964Chlorobenzene溶媒

実験手順

A mixture of 0.45 g of 4-amino-5-nitro-1H-pyridin-2-one and 0.87 g of 2-methoxy-4-methylmercapto-benzoyl chloride was refluxed for 8 hours in 10 ml of chlorobenzene. The precipitated product was suction-filtered off, washed with methylene chloride and used in the next step as the crude product without further purification.

後処理

  1. filtrationThe precipitated product was suction-filtered off
  2. washwashed with methylene chloride
  3. customused in the next step as the crude product without further purification

出典と根拠

ORDレコード
ord-945ebead078c45ba8c3174554b87020d
出典データセット
uspto-grants-1986_02
特許番号
US04568680

反応ノート

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