Bromine → HCID 70456026、化合物

HRID 1589298ノート

反応式

HRID 1589298 の反応式
[CH3:1][O:2][C:3]1[CH:8]=[C:7]([S:9][CH3:10])[CH:6]=[CH:5][C:4]=1[C:11]1[N:20]=[C:14]2[C:15](=[O:19])[NH:16][CH2:17][CH:18]=[C:13]2[N:12]=1.C([O-])(=[O:23])C.[Na+].BrBr>C(O)(=O)C>[CH3:1][O:2][C:3]1[CH:8]=[C:7]([S:9]([CH3:10])=[O:23])[CH:6]=[CH:5][C:4]=1[C:11]1[N:20]=[C:14]2[C:15](=[O:19])[NH:16][CH2:17][CH:18]=[C:13]2[N:12]=1

参加物

5

反応物 3

HCID 24408BromineHCID 517045Sodium AcetateHCID 70455630HCID 70455630、化合物

生成物 1

HCID 70456026HCID 70456026、化合物

試薬・触媒・溶媒 1

HCID 176Acetic Acid溶媒2 回

実験手順

0.3 g of 2-(2-methoxy-4-methylmercapto-phenyl)-5H-imidazo[4,5-c]pyridin-4-one were suspended in 10 ml of 50% acetic acid, and 0.2 g of anhydrous sodium acetate were added thereto. 0.15 g of bromine, dissolved in 2 ml of glacial acetic acid, was added dropwise to the mixture, while stirring. After the reaction had ended the mixture was poured over ice, and the precipitate thus obtained was recrystallized from ethanol. Melting point: 267°-272° C. (decomposition).

後処理

  1. additionwas added dropwise to the mixture
  2. additionwas poured over ice
  3. customthe precipitate thus obtained
  4. customwas recrystallized from ethanol

出典と根拠

ORDレコード
ord-fc11ee5874bc4708a1c6d4bce9ae20f3
出典データセット
uspto-grants-1986_02
特許番号
US04568680

反応ノート

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