Malononitrile → 1-cyclopropyl-4,6-diamino-2(1H)-pyrimidinethione

反応式

[CH:1]1([NH:4][C:5]([NH2:7])=[S:6])[CH2:3][CH2:2]1.[C:8](#[N:12])[CH2:9][C:10]#[N:11]>>[CH:1]1([N:4]2[C:10]([NH2:11])=[CH:9][C:8]([NH2:12])=[N:7][C:5]2=[S:6])[CH2:3][CH2:2]1

参加物

反応物 2

HCID 8010Malononitrile

HCID 2560481Cyclopropylthiourea

生成物 1

HCID 197692121-cyclopropyl-4,6-diamino-2(1H)-pyrimidinethione収率 38%

実験手順

N-cyclopropylthiourea (6.2 g) and malononitrile (6.6 g) were reacted in the same method as described in Preparation 12 to give the pale yellow above-indicated compound(3.7 g).

後処理

customas described in Preparation 12

出典と根拠

ORDレコード: ord-bdae9684b50b40ec9ccd9a5cfa9ba30a
出典データセット: uspto-grants-1993_04
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US05202315

反応ノート

読み込み中…