N-(tert-Butyloxycarbonyl)glycine N-hydroxysuccinimide ester → HCID 15940113、化合物

HRID 1590985

反応式

HRID 1590985 の反応式
[NH:1]([C:14]([O:16]C(C)(C)C)=O)[C@H:2]([C:7]([NH:9][CH2:10][C:11]([OH:13])=[O:12])=[O:8])[CH2:3][CH:4]([CH3:6])[CH3:5].[NH:21]([C:33]([O:35][C:36]([CH3:39])([CH3:38])[CH3:37])=[O:34])[CH2:22]C(ON1C(=O)CCC1=O)=O>>[NH:21]([C:33]([O:35][C:36]([CH3:39])([CH3:38])[CH3:37])=[O:34])[CH2:22][C:14]([NH:1][C@H:2]([C:7]([NH:9][CH2:10][C:11]([OH:13])=[O:12])=[O:8])[CH2:3][CH:4]([CH3:5])[CH3:6])=[O:16]

参加物

3

反応物 2

HCID 76926N-(tert-Butyloxycarbonyl)glycine N-hydroxysuccinimide esterHCID 7018768(S)-2-(2-((tert-Butoxycarbonyl)amino)-4-methylpentanamido)acetic acid

生成物 1

HCID 15940113HCID 15940113、化合物収率 61.4%

実験手順

By using 6.41 g of Boc-Leu-Gly-OH and 6.04 g of Boc-Gly-OSu, and the same procedure as in Reference Example 31 was repaeted to obtain 4.67 g (yield: 61.4%) of the above-mentioned objective product.

出典と根拠

ORDレコード
ord-dc58cf6dbd2347cdbc0bfc92af10d6c6
出典データセット
uspto-grants-1993_04
特許番号
US05204326

関連ノート

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