Acetic Acid → HCID 18947702、化合物
反応式
[Cl:1][C:2]1[CH:7]=[C:6]([Cl:8])[CH:5]=[CH:4][C:3]=1[C:9]1[NH:10]C(C#N)=[C:12]([C:14]#N)[N:13]=1.[C:18]([OH:21])(=[O:20])[CH3:19].S(=O)(=O)(O)[OH:23].[OH2:27]>>[Cl:1][C:2]1[CH:7]=[C:6]([Cl:8])[CH:5]=[CH:4][C:3]=1[C:9]1[NH:10][C:19]([C:18]([OH:21])=[O:20])=[C:12]([C:14]([OH:23])=[O:27])[N:13]=1参加物
5
実験手順
A mixture of 2-(2,4-dichlorophenyl)-4,5-dicyanoimidazole (10.05 g, 0.038 mol), glacial acetic acid (41 ml), concentrated sulphuric acid (19 ml) and water (9.4 ml) was heated at 120°-125° C. for 1.5 hours. After cooling the mixture was poured into water (300 ml) and the precipitated solid filtered off and dried in vacuo (100° C. at 50 mm Hg) to give 2-(2,4-dichlorophenyl)imidazole-4,5-dicarboxylic acid (10.24 g) m.p. 237.5°-238.5° C. as a white solid.