Hydrochloric Acid → HCID 67138330、化合物
反応式
C(OC(=O)[NH:7][CH2:8][C:9]1[CH:14]=[CH:13][C:12]([CH2:15][N:16]2[CH2:20][C:19](=[O:21])[N:18]([CH2:22][C:23]3[CH:28]=[CH:27][C:26]([O:29][CH3:30])=[CH:25][C:24]=3[O:31][CH3:32])[S:17]2(=[O:34])=[O:33])=[CH:11][CH:10]=1)(C)(C)C.[ClH:36]>CCOC(C)=O>[ClH:36].[NH2:7][CH2:8][C:9]1[CH:10]=[CH:11][C:12]([CH2:15][N:16]2[S:17](=[O:33])(=[O:34])[N:18]([CH2:22][C:23]3[CH:28]=[CH:27][C:26]([O:29][CH3:30])=[CH:25][C:24]=3[O:31][CH3:32])[C:19](=[O:21])[CH2:20]2)=[CH:13][CH:14]=1参加物
4
実験手順
The title A compound, {4-[5-(2,4-dimethoxy-benzyl)-1,1,4-trioxo-1,2,5-thiadiazolidin-2-ylmethyl]-benzyl}-carbamic acid t-butyl ester (400 mg, 0.79 mmol) is dissolved in EtOAc (20 mL) with gentle warming. The cooled solution is saturated with HCl gas and stirred for 30 min. The resulting precipitate is collected by filtration, washed with EtOAc and dried to give 5-(4-aminomethyl-benzyl)-2-(2,4-dimethoxy-benzyl)-1,1-dioxo-1,2,5-thiadiazolidin-3-one hydrochloride: [M+1]+=406.