2-(5-Trifluoromethyl-pyridin-2-YL)-ethylamine → 1-methyl-6-[2-(5-trifluoromethyl-pyridin-2-yl)-ethylamino]-3,4-dihydro-1H-quinolin-2-one

反応式

[Br:1][c:2]1[cH:3][c:4]2[c:9]([cH:10][cH:11]1)[N:8]([CH3:12])[C:7](=[O:13])[CH2:6][CH2:5]2.[F:14][C:15]([c:16]1[cH:17][cH:18][c:19]([CH2:22][CH2:23][NH2:24])[n:20][cH:21]1)([F:25])[F:26]>>[c:2]1([NH:24][CH2:23][CH2:22][c:19]2[cH:18][cH:17][c:16]([C:15]([F:14])([F:25])[F:26])[cH:21][n:20]2)[cH:3][c:4]2[c:9]([cH:10][cH:11]1)[N:8]([CH3:12])[C:7](=[O:13])[CH2:6][CH2:5]2

参加物

反応物 2

HCID 180713442-(5-Trifluoromethyl-pyridin-2-YL)-ethylamine

HCID 631061416-Bromo-1-methyl-1,2,3,4-tetrahydroquinolin-2-one

生成物 1

HCID 580075951-methyl-6-[2-(5-trifluoromethyl-pyridin-2-yl)-ethylamino]-3,4-dihydro-1H-quinolin-2-one

出典と根拠

ORDレコード: ord-574732838a7d4a93b5b1eb215fedd035
出典データセット: Training data from https://doi.org/10.1039/C8SC04228D (9/10)
DOI: 10.1039/C8SC04228D

反応ノート

読み込み中…