Triacetoxyperiodinane → HCID 86603571、化合物

HRID 1593016ノート

反応式

HRID 1593016 の反応式
[C:1]1([C@@H:7]([C:11]2[CH:16]=[CH:15][C:14]([S:17]([CH3:20])(=[O:19])=[O:18])=[CH:13][CH:12]=2)[CH2:8][CH2:9][OH:10])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.CC(OI1(OC(C)=O)(OC(C)=O)OC(=O)C2C=CC=CC1=2)=O>C(Cl)Cl>[C:1]1([C@@H:7]([C:11]2[CH:12]=[CH:13][C:14]([S:17]([CH3:20])(=[O:19])=[O:18])=[CH:15][CH:16]=2)[CH2:8][CH:9]=[O:10])[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

参加物

4

反応物 2

HCID 159087TriacetoxyperiodinaneHCID 69264553(γS)-4-(Methylsulfonyl)-γ-phenylbenzenepropanol

生成物 1

HCID 86603571HCID 86603571、化合物

試薬・触媒・溶媒 1

HCID 6344Dichloromethane溶媒

実験手順

To a solution of (S)-3-phenyl-3-(4-methanesulfonylphenyl)propan-1-ol (244 mg, 0.84 mmol) in DCM (5 mL) was added Dess-Martin periodinane (392 mg, 0.92 mmol) and the resulting mixture was stirred at room temperature for 1.5 h. The mixture was washed with 2M aqueous sodium hydroxide (2×10 mL), dried and evaporated to give the title compound.

後処理

  1. washThe mixture was washed with 2M aqueous sodium hydroxide (2×10 mL)
  2. customdried
  3. customevaporated

出典と根拠

ORDレコード
ord-ae52171f0fbc435fa9f81d6f147975ad
出典データセット
uspto-grants-2007_11
特許番号
US07294636B2

反応ノート

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